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Related Experiment Videos

Papillary eccrine adenoma.

P H Cooper, H F Frierson

    Archives of Pathology & Laboratory Medicine
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Papillary eccrine adenoma is a benign skin tumor with distinctive microscopic features. This case highlights its unique cellular structure and stromal characteristics.

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    In Reply.

    Archives of pathology & laboratory medicine·2026
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    Area of Science:

    • Dermatopathology
    • Oncology

    Background:

    • Papillary eccrine adenoma (PEA) is a rare, benign cutaneous neoplasm.
    • Understanding its histopathological and clinical features is crucial for accurate diagnosis.

    Observation:

    • Microscopic examination revealed multiple ducts with stratified cells forming papillae.
    • The stroma showed loose spindled cells and hyalinized collagen bands surrounding ducts.
    • Focal squamous differentiation, clear cell change, epidermal connections, and prominent nerves were noted.

    Findings:

    • The study details the characteristic microscopic appearance of papillary eccrine adenoma.
    • Observed features include papillary projections, specific stromal components, and rare cellular changes.
    • Clinical presentation involves firm nodules, often on extremities, particularly in individuals of color.

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    Implications:

    • Accurate identification of PEA aids in differentiating it from malignant adnexal tumors.
    • This case contributes to the understanding of the histopathological spectrum of PEA.
    • Awareness of clinical associations can assist in early detection and diagnosis.