Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Computer program for calculating recombination values from electrophoretic data.

A Hakim-Elahi

    The Journal of Heredity
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same journal

    Chromosome-scale genome assembly of the rice stink bug (Hemiptera: Oebalus pugnax) illuminates genome structure and gene family evolution in Pentatomidae.

    The Journal of heredity·2026
    Same journal

    Rapid Derivation of Cloning-Competent Cells from Peripheral Blood Advances Conservation Biobanking.

    The Journal of heredity·2026
    Same journal

    Genomic vulnerability to climate change of a poorly dispersing and threatened fish, the southern pygmy perch (Nannoperca australis).

    The Journal of heredity·2026
    Same journal

    The complete genomes of two hybridizing field crickets, Gryllus pennsylvanicus and Gryllus firmus.

    The Journal of heredity·2026
    Same journal

    Chromosome-level genome assembly and annotation of the transverse lady beetle Coccinella transversoguttata.

    The Journal of heredity·2026
    Same journal

    A Chromosome-Level Assembly of the Pine Processionary Moth (Thaumetopoea pityocampa) genome.

    The Journal of heredity·2026

    A new FORTRAN program estimates genetic recombination values from F2 data. This tool calculates recombination frequencies between gene loci using maximum likelihood estimation for genetic mapping studies.

    Area of Science:

    • Genetics
    • Bioinformatics
    • Computational Biology

    Background:

    • Estimating recombination values is crucial for genetic mapping and understanding genome organization.
    • Existing methods may require specific data formats or computational resources.
    • Accurate recombination data aids in constructing genetic maps and identifying gene linkage.

    Purpose of the Study:

    • To develop a versatile FORTRAN computer program for calculating recombination values from F2 genotypic data.
    • To provide a method for estimating recombination frequencies between any number of loci across multiple F2 families.
    • To incorporate statistical measures like standard error and chi-square for data homogeneity assessment.

    Main Methods:

    • Development of a FORTRAN program utilizing maximum likelihood estimation.

    Related Experiment Videos

  • Inputting codominant allele data from multiple F2 families segregating for numerous loci.
  • Calculating a single recombination value and its standard error for each locus pair.
  • Reporting chi-square for homogeneity when data from multiple families are combined.

    • Main Results:

    • The program successfully calculates recombination values from F2 data.
    • It handles any number of loci and F2 families, limited only by computer memory.
    • Maximum likelihood estimation provides accurate recombination values with standard errors.
    • Chi-square values indicate data homogeneity across different families.

    Conclusions:

    • The developed FORTRAN program offers an efficient and flexible tool for genetic recombination analysis.
    • It facilitates the estimation of genetic distances and linkage relationships in F2 populations.
    • The program's ability to integrate data from multiple families enhances the robustness of recombination estimates.