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Updated: Aug 16, 2026

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Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
Published on: February 27, 2011
Evidence for multiple muscarinic receptor subtypes in human brain
Journal of Neurochemistry
|August 1, 1984
Abstract:
Pirenzepine, a compound with selective antimuscarinic activity, was used to distinguish muscarinic acetylcholine receptor subtypes in normal human brain. Hill coefficients and IC50 values derived from the inhibition of specific [3H]L-quinuclidinyl benzilate receptor binding suggest the presence of two muscarinic binding sites, differing both in affinity for pirenzepine and in tissue distribution.
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