Experience with NONMEM: analysis of serum concentration data in patients treated with mexiletine and lidocaine
Drug Metabolism Reviews
|January 1, 1984
Abstract:
The generality and flexibility of the computer package NONMEM also confront the user with the difficult task of choosing the model which best describes the data at hand. With two practical examples we show how one may proceed in building the population model for serum concentration measurements. Features of NONMEM are presented which help the user to make the choice among different models.
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