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[Quantification of myocardial perfusion defects using 2-dimensional contrast echocardiography]
Zeitschrift Fur Kardiologie
|September 1, 1984
Summary
New ultrasonic contrast agent Echocon enables reproducible myocardial contrast imaging. This technique successfully diagnosed perfusion defects, aiding coronary heart disease diagnosis.
Area of Science:
- Cardiovascular imaging
- Diagnostic ultrasound
- Myocardial perfusion assessment
Context:
- Coronary heart disease diagnosis remains challenging.
- Echocardiography offers non-invasive assessment potential.
- Novel contrast agents are needed for enhanced myocardial visualization.
Purpose:
- To evaluate Echocon for reproducible myocardial contrast imaging.
- To assess the diagnostic accuracy of Echocon-enhanced echocardiography for myocardial perfusion defects.
- To determine the safety and hemodynamic effects of Echocon injection.
Summary:
- Ten beagles underwent aortic root injection of Echocon for myocardial contrast imaging.
- Myocardial contrast intensity was measured during coronary artery occlusion.
- Echocon demonstrated reproducible imaging and accurately identified perfusion defects (r=0.89).
Impact:
- Echocon facilitates reproducible myocardial echocontrast imaging.
- Contrast echocardiography with Echocon can aid in diagnosing coronary heart disease.
- The method showed no significant adverse hemodynamic effects.