Absence of day to day variation in lymphocyte subpopulations in healthy humans

Lymphocyte subpopulations were determined by indirect immunofluorescence using monoclonal antibodies T11, T4, T8 and B1 on three different days in a group of thirteen normal subjects. Although there was considerable intersubject variation, the percentages of lymphocyte subpopulations as well as absolute numbers did not differ within the same subject over the three days tested, showing that lymphocyte subpopulation proportions and absolute numbers are stable characteristics of the healthy subject.