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Abstract:
We have studied 17 cases of pseudomycotic onychoses. This condition is frequently seen in the toe nails with the clinical aspect of hyperkeratosis of the nail bed and onycholysis. The Giemsa stained preparations have been performed with the clinical material previously heated in a 40% OHK solution and washed out with distilled water by centrifugation. The microorganism has similar or identical characteristics to those of the agent of erythrasma of the folds. Its morphology and physiological characteristics are comcon to "Corynebacterium" and "Nocardia". It is a gram positive, acid-fast organism with tendency to produce filaments with short lateral branches and fragmentation spores. Indirect inmunofluorescence identifies microorganisms present in the clinical material and that obtained in cultures.
Insights
This study identifies a microorganism causing pseudomycotic onychoses, a nail condition characterized by hyperkeratosis and onycholysis. The organism shares traits with Corynebacterium and Nocardia, aiding in diagnosis.
Area of Science:
- Medical Mycology
- Dermatology
- Microbiology
Background:
- Pseudomycotic onychoses are fungal-like nail infections.
- This study investigates 17 cases presenting with nail bed hyperkeratosis and onycholysis, primarily affecting toenails.
Observation:
- Microscopic examination utilized Giemsa staining on heated clinical samples.
- The causative microorganism exhibited gram-positive, acid-fast properties.
- Morphological and physiological characteristics were consistent with Corynebacterium and Nocardia species.
Findings:
- The microorganism demonstrated filament formation with branching and fragmentation into spores.
- Indirect immunofluorescence confirmed the presence of the organism in both clinical samples and cultures.
- The identified agent shares similarities with the causative agent of erythrasma.
Implications:
- Accurate identification of this microorganism is crucial for effective treatment of pseudomycotic onychoses.
- Understanding its characteristics aids in differential diagnosis from other nail disorders.
- Further research into this organism may reveal novel therapeutic targets.