Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Severe steroid-responsive nephrosis associated with hypersensitivity.

D H Sandberg, C W Bernstein, R M McIntosh

    Lancet (London, England)
    |February 19, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Search for new phenomena with the <math></math> variable in the all-hadronic final state produced in proton-proton collisions at <math> </math> <math></math>.

    The European physical journal. C, Particles and fields·2020
    Same author

    Measurement of the triple-differential dijet cross section in proton-proton collisions at <math> </math> and constraints on parton distribution functions.

    The European physical journal. C, Particles and fields·2020
    Same author

    Measurements of the associated production of a Z boson and b jets in pp collisions at <math> </math>.

    The European physical journal. C, Particles and fields·2020
    Same author

    Search for dark matter produced in association with heavy-flavor quark pairs in proton-proton collisions at <math> </math>.

    The European physical journal. C, Particles and fields·2020
    Same author

    Study of dijet events with a large rapidity gap between the two leading jets in pp collisions at <math> </math> <math></math>.

    The European physical journal. C, Particles and fields·2019
    Same author

    Measurement of associated Z + charm production in proton-proton collisions at <math> </math> <math></math>.

    The European physical journal. C, Particles and fields·2019
    Same journal

    Assisted dying and the silencing of medicine's next generation.

    Lancet (London, England)·2026
    Same journal

    Linguistic pragmatism: a woman with progressive abdominal pain in Thailand.

    Lancet (London, England)·2026
    Same journal

    Medical compartmentalisation: a patient with chromosome 22q11.2 deletion syndrome in Japan.

    Lancet (London, England)·2026
    Same journal

    [<sup>177</sup>Lu]Lu-edotreotide versus everolimus for gastroenteropancreatic neuroendocrine tumours (COMPETE): a phase 3, multicentre, randomised, open-label, superiority trial.

    Lancet (London, England)·2026
    Same journal

    Research priorities for characterising Bundibugyo virus.

    Lancet (London, England)·2026
    Same journal

    Rethinking treatment sequence in advanced gastroenteropancreatic neuroendocrine tumours.

    Lancet (London, England)·2026
    See all related articles

    Food allergies may trigger childhood nephrotic syndrome. Cow

    Area of Science:

    • Pediatric Nephrology
    • Clinical Immunology
    • Allergy and Immunology

    Background:

    • Idiopathic nephrotic syndrome (INS) is a significant kidney disorder in children.
    • The etiology of INS is often unclear, but immune system dysregulation is implicated.
    • Dietary factors are increasingly being explored as potential triggers for chronic conditions.

    Purpose of the Study:

    • To investigate the potential role of cow's whole milk hypersensitivity in pediatric idiopathic nephrotic syndrome.
    • To determine if dietary challenges with cow's milk can elicit nephrotic syndrome relapse.
    • To explore immunological markers associated with milk challenge in these patients.

    Main Methods:

    • Six patients with INS were placed on an elemental diet until proteinuria resolved.

    Related Experiment Videos

  • Patients underwent a cow's milk challenge, and clinical and biochemical parameters were monitored.
  • Intradermal skin testing with cow's milk extract was performed on all participants.

    • Main Results:

    • Four out of six patients experienced relapse of proteinuria, edema, and decreased urine output after cow's milk challenge.
    • Serum IgG concentrations decreased in four patients post-challenge.
    • All six patients showed acute alterations in plasma C3 complement component and positive skin tests to cow's milk.

    Conclusions:

    • Cow's milk hypersensitivity may be a contributing factor to the clinical and biochemical manifestations of idiopathic nephrotic syndrome in some children.
    • Food allergies should be considered in the differential diagnosis and management of recurrent or persistent nephrotic syndrome.
    • Further research is warranted to elucidate the mechanisms linking food hypersensitivity and nephrotic syndrome.