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Related Experiment Videos

Skeletal changes in preterm infants: personal experience.

N Colavita, M Marconi, C Orazi

    Diagnostic Imaging in Clinical Medicine
    |January 1, 1984
    PubMed
    Summary
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    Skeletal changes in preterm infants are increasing. Radiology can detect rickets, but bone densitometry is better for early osteoporosis detection in these vulnerable infants.

    Area of Science:

    • Neonatalogy
    • Pediatric Radiology
    • Skeletal Development

    Background:

    • Rising incidence of skeletal abnormalities in preterm, low-birth-weight infants.
    • Increased survival rates of high-risk neonates contribute to this trend.
    • Biochemical markers and clinical signs for skeletal pathology in neonates are often non-specific or delayed.

    Purpose of the Study:

    • To evaluate the utility of radiological methods in diagnosing skeletal pathology in preterm infants.
    • To compare the sensitivity of radiology versus densitometry for detecting osteopenia and rickets.
    • To propose a follow-up strategy for skeletal assessment in preterm infants.

    Main Methods:

    • Retrospective analysis of 8 preterm infants with documented skeletal pathology.

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  • Review of radiological findings, including X-rays.
  • Comparison of radiological assessment with biochemical data and clinical presentation.

    • Main Results:

    • Radiology effectively identified rachitic changes in preterm infants.
    • Radiological methods showed limited sensitivity in detecting minimal osteoporotic changes.
    • Densitometric studies are recommended for more accurate assessment of osteopenia.

    Conclusions:

    • Radiology plays a role in identifying overt skeletal changes like rickets in preterm infants.
    • Densitometry is superior for detecting early or subtle osteoporotic modifications.
    • A suggested radiological skeletal follow-up from 5 to 12 weeks of life is proposed in the absence of densitometry.