[Type A adenocarcinoma grafted into C3H/he-M mice subjected to treatment with various antineoplastic agents. I....

The biological modifications in C3H/he-M mice treated with vincristine, prospidium chloride and adriamycin are studied. A significative reduction of the tumor volume was observed with prospidium chloride and adriamycin treatment. The index of tumour growth inhibition (I0) is very high and corroborates the obtained results. The histopathological and ultrastructural studies will be published later.