Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A Hamilton subscale for endogenomorphic depression.

M E Thase

    The Hillside Journal of Clinical Psychiatry
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    A new scale for endogenomorphic depression effectively differentiated subtypes in women, predicting diagnostic classifications and symptom severity. This tool aids in understanding depression

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Anatomical and fMRI-network comparison of multiple DLPFC targeting strategies for repetitive transcranial magnetic stimulation treatment of depression.

    Brain stimulation·2021
    Same author

    Targeting location relates to treatment response in active but not sham rTMS stimulation.

    Brain stimulation·2021
    Same author

    Obesity, but not metabolic syndrome, negatively affects outcome in bipolar disorder.

    Acta psychiatrica Scandinavica·2015
    Same author

    Medication adherence in a comparative effectiveness trial for bipolar disorder.

    Acta psychiatrica Scandinavica·2013
    Same author

    Using comparative effectiveness design to improve the generalizability of bipolar treatment trials data: contrasting LiTMUS baseline data with pre-existing placebo controlled trials.

    Journal of affective disorders·2013
    Same author

    Gene-expression differences in peripheral blood between lithium responders and non-responders in the Lithium Treatment-Moderate dose Use Study (LiTMUS).

    The pharmacogenomics journal·2013

    Area of Science:

    • Psychiatry
    • Clinical Psychology
    • Mental Health Research

    Background:

    • Depression diagnosis often relies on symptom clusters.
    • Distinguishing between endogenous and nonendogenous depression is clinically relevant.
    • The Hamilton Rating Scale for Depression (HRSD) is a widely used depression assessment tool.

    Purpose of the Study:

    • To validate a new scale measuring endogenomorphic depression, derived from the HRSD.
    • To assess the scale's ability to predict diagnostic classifications and symptom severity.
    • To explore the clinical utility of endogenomorphic depression assessment.

    Main Methods:

    • A cohort of 147 women outpatients with primary depression was studied.
    • An endogenomorphic depression scale was administered.

    Related Experiment Videos

  • Diagnostic predictions were made using Research Diagnostic Criteria (RDC) and DSM-III criteria.
  • Symptomatology and social impairment were measured.

    • Main Results:

    • Endogenomorphicity scores showed a bimodal distribution, with 53% high and 47% low.
    • The scale's cutting point significantly predicted RDC (81%) and DSM-III (64%) diagnoses.
    • Individuals with high endogenomorphicity scores exhibited greater depressive symptomatology and social impairment.

    Conclusions:

    • The derived endogenomorphic depression scale demonstrates validity in differentiating depression subtypes.
    • The scale shows potential for predicting diagnostic classifications and identifying patients with higher symptom burden.
    • Further research and clinical applications of this scale are warranted.