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Related Experiment Videos

The ventricular-brain ratio on computed tomography scans: validity and proper use.

L M Zatz, T L Jernigan

    Psychiatry Research
    |March 1, 1983
    PubMed
    Summary

    Planimetric measurement of ventricular size using computed tomography is a useful, accessible method. However, the ventricular-brain ratio may be inappropriate for childhood-acquired conditions, necessitating guidelines for accurate assessment.

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    Area of Science:

    • Neuroradiology
    • Neuroimaging analysis
    • Quantitative anatomy

    Background:

    • Planimetric measurement of ventricular area on computed tomography (CT) scans offers a practical approach to assess ventricular size.
    • This method is often reported as a planimetric ventricular-brain ratio (VBR).
    • The rationale for using a ratio stems from the established relationship between ventricular and cranial size in healthy adults.

    Purpose of the Study:

    • To evaluate the utility and limitations of planimetric ventricular-brain ratio (VBR) measurements.
    • To provide recommendations for the appropriate application of planimetric methods in neuroimaging.
    • To address potential biases in experimental results when assessing ventricular size.

    Main Methods:

    • Utilizing computed tomographic (CT) sections for planimetric area measurements of brain ventricles.

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  • Calculating the ventricular-brain ratio (VBR) as a measure of ventricular size.
  • Reviewing existing literature and clinical data to assess the VBR's applicability across different age groups and conditions.

    • Main Results:

    • Planimetric VBR is a convenient and useful method for assessing ventricular size, especially when advanced techniques are unavailable.
    • The VBR may not be a suitable metric for conditions acquired during childhood due to altered scaling relationships.
    • Potential biases in experimental results can arise from the inappropriate application of VBR.

    Conclusions:

    • Planimetric ventricular area measurement is a valuable tool in neuroimaging.
    • Guidelines are proposed to ensure the accurate and unbiased use of planimetric methods, particularly the VBR.
    • Careful consideration of the VBR's limitations is crucial, especially in pediatric neuroimaging studies.