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Updated: Aug 9, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Acute nonlymphocytic leukemia and acute aplastic anemia. The simultaneous occurrence in marital partners
Abstract:
A young husband and wife couple presented simultaneously with aplastic anemia and acute myelomonocytic leukemia, respectively. No etiologic agent or exposure was identified. With appropriate therapy, the wife achieved a complete remission and the husband has had a good response. Potential etiologic environmental factors known to cause both disorders are discussed. A single causative agent may induce stem-cell changes in genetically dissimilar persons and produce a spectrum of pathologic features ranging from aplastic anemia to acute leukemia.
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