Menstrual pattern and fertility after treatment for anovulatory infertility

Sixty-four patients who had been treated for anovulatory infertility and subsequently conceived were reviewed. Information was obtained on subsequent menstrual pattern, contraception used, treatment required to achieve a further pregnancy and the interval to any such pregnancy. Almost half the group had regular cycles following delivery but 2 patients had a recurrence of post oral contraceptive amenorrhoea. Most patients conceived without treatment within 2 years of the initial pregnancy but 10 again required ovulation induction. It is concluded that there is no long-term irreversible suppression of hypothalamic function in this group of patients and, once a pregnancy has been achieved, the prognosis for future fertility without therapy is good.