Enamel fluoride content after using amine fluoride- or monofluorophosphate-sodium fluoride-dentifrices

Area of Science:

• Dental materials science
• Cariology
• Fluoride chemistry

Background:

• Fluoride dentifrices are crucial for caries prevention.
• Different fluoride compounds may vary in their efficacy for enamel fluoride uptake.
• Understanding enamel fluoride retention is key to optimizing anti-caries strategies.

Purpose of the Study:

• To compare in vivo fluoride retention in enamel between amine fluoride and monofluorophosphate-sodium fluoride dentifrices.
• To assess the impact of these dentifrices on enamel dissolution and etching.

Main Methods:

• A double-blind, in vivo study design was employed.
• Acid-etch enamel biopsies were used to quantify fluoride content.
• Enamel dissolution was measured by phosphorus levels, and etch depth was determined.

Main Results:

• Amine fluoride dentifrice resulted in significantly higher enamel fluoride content (959 ppm F) compared to monofluorophosphate-sodium fluoride (330 ppm F).
• Enamel dissolution, indicated by phosphorus levels, was significantly reduced with amine fluoride (33.9 µg vs 50.9 µg).
• Etch depth was also significantly lower after using amine fluoride (6.2 µm vs 9.6 µm).

Conclusions:

• Amine fluoride dentifrices demonstrate superior performance in enhancing enamel fluoride retention compared to monofluorophosphate-sodium fluoride.
• Amine fluoride offers enhanced protection against enamel demineralization and acid erosion.
• These findings support the use of amine fluoride in dentifrices for improved dental caries prevention.