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Peripheral calcifying epithelial odontogenic tumor.

Y Takeda, A Suzuki, S Sekiyama

    Oral Surgery, Oral Medicine, and Oral Pathology
    |July 1, 1983
    PubMed
    Summary
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    Peripheral calcifying epithelial odontogenic tumors (CEOT) are rare, often originating centrally in the jaw. This case highlights gingival epithelium as a potential source for peripheral CEOT development.

    Area of Science:

    • Oral pathology
    • Odontogenic neoplasms
    • Gingival pathology

    Background:

    • Calcifying epithelial odontogenic tumors (CEOT) are rare odontogenic neoplasms, typically presenting as central jaw lesions.
    • Peripheral CEOT, occurring outside the bone on the gingiva, is exceptionally infrequent.
    • Understanding the origin of peripheral CEOT is crucial for accurate diagnosis and management.

    Observation:

    • A case of peripheral CEOT in the right upper molar gingiva of a 31-year-old Japanese woman is presented.
    • Serial section examination revealed direct communication between the overlying gingival epithelium and the tumor.
    • This anatomical connection suggests a link between the tumor and the gingival epithelium.

    Findings:

    • The gingival epithelium overlying the peripheral CEOT demonstrated potential proliferative activity.

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  • A direct epithelial connection supports the hypothesis that gingival epithelium can be a source of peripheral CEOT.
  • This finding challenges the traditional view of CEOT originating solely centrally within the jaws.

    • Implications:

    • Gingival epithelium should be considered a potential origin for peripheral calcifying epithelial odontogenic tumors.
    • This expands the differential diagnosis for gingival masses and odontogenic lesions.
    • Further research into the proliferative capacity of gingival epithelium in CEOT development is warranted.