Translocation (15;17) in a child with variant form of acute promyelocytic leukemia

We present the cytogenetic and hematologic study of a 6-year-old child with a variant form of acute promyelocytic leukemia (M3) who died of a brain hemorrhage. The brief survival and the hyperleukocytosis (greater than 200,000 mm3) suggests a very bad prognosis in children with this variant form of M3 leukemia.