Acute myeloblastic leukemia (AML) with t(6;9) (p23;q34): a specific subgroup of AML?

A case of acute myeloblastic leukemia (AML) of M2 type in the FAB classification without Auer bodies in the leukemic cells was shown to have t(6;9)(p23;q34) in the marrow cells. Four hematologically similar cases with identical karyotype changes have been published. We propose, in support of others, that this may constitute a subgroup of AML characterized by a translocation between chromosome #6 and #9.