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Related Experiment Videos

Psoriasis and arthritis.

T F Anderson, J J Voorhees

    Cutis
    |June 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Psoriatic arthritis, a controversial condition, affects a small percentage of psoriasis patients. Evidence suggests its prognosis may be better than previously thought, with various therapeutic measures available.

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    Area of Science:

    • Rheumatology
    • Dermatology
    • Immunology

    Background:

    • The link between psoriasis and arthritis remains debated.
    • Psoriatic arthritis affects approximately 7% of psoriasis patients, often presenting as sero-negative inflammatory polyarthritis.
    • A distinct peripheral arthropathy occurs in 1% of psoriasis patients, with a small fraction developing deforming arthritis mutilans.

    Purpose of the Study:

    • To review evidence for and against psoriatic arthropathy as a distinct entity.
    • To evaluate the current understanding of its epidemiology, clinical presentation, radiology, serology, and genetics.
    • To assess the prognosis and review therapeutic interventions for psoriatic arthritis.

    Main Methods:

    • Comprehensive literature review of epidemiologic, clinical, radiologic, serologic, and genetic studies.

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  • Analysis of existing data on psoriatic arthropathy prevalence and characteristics.
  • Synthesis of information on treatment outcomes and patient prognosis.

    • Main Results:

    • Psoriatic arthritis is observed in a minority of psoriasis patients, with varying clinical and radiographic features.
    • Evidence supporting psoriatic arthropathy as a unique entity is presented and discussed.
    • The prognosis for psoriatic arthritis appears more favorable than previously reported.

    Conclusions:

    • Psoriatic arthropathy is a complex condition with a spectrum of presentations.
    • Further research is warranted to fully elucidate its unique characteristics and optimize management.
    • Current therapeutic strategies offer potential for improved patient outcomes.