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Antimicrobial prescribing errors in children.

K Grimwood, J J Cook, G D Abbott

    The New Zealand Medical Journal
    |October 26, 1983
    PubMed
    Summary
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    Pediatric antimicrobial prescribing had significant errors, especially in community settings. Inappropriate drug choices and dosages were common, necessitating improved antibiotic stewardship in children.

    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Pharmacology

    Background:

    • Antimicrobial agents are frequently prescribed for pediatric infections.
    • Assessing the appropriateness of antimicrobial prescribing is crucial for patient outcomes and combating resistance.

    Purpose of the Study:

    • To evaluate the appropriateness of antimicrobial prescribing in hospitalized children and those treated in the community.
    • To identify common errors in pediatric antimicrobial therapy.

    Main Methods:

    • A retrospective review of patient charts over a 120-day period.
    • Analysis of 255 pediatric patients receiving antimicrobial agents.
    • Categorization of prescribing errors, including dosage, duration, and drug choice.

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    Main Results:

    • 64% of hospital-prescribed antimicrobials were appropriate; major errors involved dosage, particularly with aminoglycosides and chloramphenicol.
    • Only 11% of community-prescribed antimicrobials were appropriate or error-free.
    • Common errors in the community included prescribing for viral infections and incorrect dosage, duration, and drug selection.

    Conclusions:

    • Significant discrepancies exist in the appropriateness of antimicrobial prescribing between hospital and community settings for pediatric patients.
    • Errors in pediatric antimicrobial prescribing, especially in the community, are frequent and require targeted interventions to improve antibiotic stewardship.