Guide to the analysis of phencyclidine and its metabolites in biological material

Phencyclidine was introduced as an anaesthetic in 1960; and has now become a major drug of abuse in some countries. The rapid advance in the various fields of analytical chemistry during the past decades has made it possible to measure the levels of the compounds in tissues and body fluids. These methods may also be used to study the metabolism and pharmacokinetics of PCP. The resulting publication is an updated guide to these analyses particularly with the application of these techniques in human intoxication.