Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Osteogenic sarcoma in the American black.

A G Huvos, A Butler, S S Bretsky

    Cancer
    |November 15, 1983
    PubMed
    Summary

    Osteogenic sarcoma (bone cancer) is increasingly affecting Black patients, who are diagnosed younger. However, survival rates for Black and White patients are similar, challenging general cancer outcome disparities.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Post-transplant lymphoproliferative disorder following multivisceral transplantation: Incidence, risk factors, and outcomes in an adult UK cohort.

    Intestinal Failure (New York, N.Y.)·2026
    Same author

    Pro-arrhythmic effects of gain-of-function potassium channel mutations in the short QT syndrome.

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2023
    Same author

    Review: Preference elicitation methods for appropriate breeding objectives.

    Animal : an international journal of animal bioscience·2022
    Same author

    Carbon dioxide levels in neonates: what are safe parameters?

    Pediatric research·2021
    Same author

    Characteristics of a later life population in a general adult community mental health service setting.

    Irish journal of psychological medicine·2021
    Same author

    Imaging of adult intestinal failure.

    Clinical radiology·2019

    Area of Science:

    • Orthopedic Oncology
    • Medical Statistics
    • Epidemiology

    Background:

    • Osteogenic sarcoma (bone cancer) incidence and outcomes historically show racial disparities.
    • Understanding demographic trends and clinical characteristics in osteogenic sarcoma is crucial for targeted treatment and research.

    Purpose of the Study:

    • To analyze the clinicopathologic features and survival outcomes of osteogenic sarcoma in American Black patients.
    • To compare these findings with White patients to identify any racial differences in disease presentation and prognosis.

    Main Methods:

    • Clinicopathologic review of 100 American Black patients diagnosed with osteogenic sarcoma between 1921-1979.
    • Comparative analysis of demographic, clinical, radiographic, and survival data between Black and White patient cohorts.

    Main Results:

    • A notable increase in osteogenic sarcoma cases among Black patients, particularly in the 1970s.
    • Black patients were diagnosed at a younger age compared to White patients, especially Black girls.
    • Similar skeletal tumor locations and histologic subtypes were observed, with tibia/fibula more frequent in Black patients.
    • Disease-free survival rates at 2 and 5 years were 42% and 32%, respectively, with no significant survival difference between Black and White patients.

    Conclusions:

    • Osteogenic sarcoma incidence is rising in the Black population, with earlier age of onset.
    • Despite demographic differences, Black patients with osteogenic sarcoma experience comparable survival rates to White patients.
    • The general trend of poorer cancer prognosis in Black individuals does not extend to osteogenic sarcoma.

    Related Experiment Videos