Lipid composition of human labial salivary gland secretions

Extraction of the dialysed and lyophilized labial saliva with chloroform/methanol yielded 423.8 +/- 73.0 micrograms of lipids/ml of saliva, a level 4-5 times higher than in the major salivary glands. Of the total lipids, 32.4 per cent were represented by neutral lipids, 44.6 per cent by glycolipids and 23.0 per cent by phospholipids. Neutral lipids had a high content of free fatty acids (43.8 per cent), cholesteryl esters (26.9 per cent) and triglycerides (15.4 per cent). The glycolipids consisted mainly of neutral (74.6 per cent) and sulphated (25.4 per cent) glyceroglucolipids, whereas phosphatidylethanolamine, phosphatidylcholine, sphingomyelin and phosphatidylserine accounted for 54.7 per cent of the total phospholipids.