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Updated: Aug 24, 2026

09:45
Histological Quantification of Chronic Myocardial Infarct in Rats
Published on: December 11, 2016
[Late morphologic changes in the myocardia of experimental animals following chronic wofatox poisoning]
Abstract:
The authors examined the morphologic changes in the myocardium of male white rats one and two months after chronic intoxication with the preparation BOFATOX, used in doses of 1/20 and 1/100 of LD50 for a period of two and four months. They observed circulatory and dystrophic changes during the first month, but after prolongation of repapatory period up to two months found definite pathologic changes, manifested by small cicatrixes, focal granuloma, vascular sclerosis and the presence of slightly manifested regenerative processes.

