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Gingiva as a site for xenobiotic metabolism in rats
Archives of Oral Biology
|January 1, 1984
Abstract:
NADPH-dependent N-demethylation of aminopyrine and tripelennamine and hydroxylation of aniline, phenytoin and tripelennamine occurred in rat gingival homogenates. The metabolic profile in gingiva appeared to be similar to that in liver, the major organ in the body for the metabolism of these xenobiotics.