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A case of erythroleukaemia with homogeneously staining regions on chromosomes
A case of erythroleukaemia with homogeneously staining regions on chromosomes is described. The number of chromosomes in bone marrow cells varied from 41 to 46 with a mode of 43. A variety of structural and numerical chromosomal abnormalities was observed. Two marker chromosomes with homogeneously staining regions were found in all aneuploid cells examined. Intensive chemotherapy failed to induce a remission and the patient died 3.9 months after diagnosis. The relation of the homogeneously staining regions on chromosomes to the two courses of chemotherapy prior to cytogenetic study is discussed.
A case of erythroleukaemia with homogeneously staining regions on chromosomes is described. The number of chromosomes in bone marrow cells varied from 41 to 46 with a mode of 43. A variety of structural and numerical chromosomal abnormalities was observed. Two marker chromosomes with homogeneously staining regions were found in all aneuploid cells examined. Intensive chemotherapy failed to induce a remission and the patient died 3.9 months after diagnosis. The relation of the homogeneously staining regions on chromosomes to the two courses of chemotherapy prior to cytogenetic study is discussed.