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Oral Candida in children.

I Berdicevsky, H Ben-Aryeh, R Szargel

Oral Surgery, Oral Medicine, and Oral Pathology

|January 1, 1984

Summary

This summary is machine-generated.

Oral Candida colonization increases with age in healthy children, affecting 45% of younger children and 65% of older children. Salivary IgA levels were higher in older children but did not correlate with Candida carriage.

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Area of Science:

Oral microbiology
Pediatric immunology
Infectious diseases

Background:

Candida species are common commensals in the human oral cavity.
Understanding the prevalence and influencing factors of oral Candida colonization in children is crucial for pediatric health.
Age-related changes in oral microflora and immune responses may impact Candida carriage.

Purpose of the Study:

To determine the prevalence of oral Candida colonization in healthy children aged 3 to 12 years.
To investigate the relationship between age, sex, and oral Candida carriage.
To explore the association between salivary immunoglobulin A (IgA) concentration, salivary electrolytes, and Candida colonization.

Main Methods:

A cross-sectional study involving 140 healthy children aged 3 to 12 years.

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Oral examination for the presence of Candida.

Measurement of salivary IgA concentration and electrolyte levels.

Main Results:

Candida colonization was detected in 45% of children aged 3-5.5 years and 65% of children aged 6-12 years (p < 0.05).
No significant sex-based difference in Candida carriage was observed.
Salivary IgA concentration was significantly higher in older children (6-12 years) (0.02 < p < 0.05) but showed no significant difference between Candida carriers and non-carriers.
Salivary electrolyte concentrations were similar in Candida-positive and Candida-negative children.

Conclusions:

Oral Candida colonization prevalence increases with age in healthy children.
While salivary IgA levels increase with age, they do not appear to be a primary factor differentiating Candida carriers from non-carriers in this pediatric population.
Further research may elucidate other age-dependent factors influencing oral Candida colonization.