Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fluphenazine and multifocal tic disorders.

C G Goetz, C M Tanner, H L Klawans

    Archives of Neurology
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Incidence of Parkinson disease in North America.

    NPJ Parkinson's disease·2022
    Same author

    Prevalence of Parkinson's disease across North America.

    NPJ Parkinson's disease·2018
    Same author

    Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.

    Movement disorders : official journal of the Movement Disorder Society·2017
    Same author

    Marinesco bodies and substantia nigra neuron density in Parkinson's disease.

    Neuropathology and applied neurobiology·2017
    Same author

    Revue neurologique·2017
    Same author

    Charcot, hysteria, and simulated disorders.

    Handbook of clinical neurology·2016
    Same journal

    Incorrect Table Entries and Word.

    Archives of neurology·2016
    Same journal

    IDEAL for CCSVI Research-Reply.

    Archives of neurology·2013
    Same journal

    Atlas of Inherited Metabolic Diseases, 3rd ed.

    Archives of neurology·2013
    Same journal

    Error in byline: in heterogeneity of coenzyme q10 deficiency: patient study and literature review.

    Archives of neurology·2013
    Same journal

    This month in archives of neurology.

    Archives of neurology·2013
    Same journal

    About this journal.

    Archives of neurology·2013
    See all related articles

    Fluphenazine hydrochloride offers an effective alternative for patients with multiple tic disorder who cannot tolerate haloperidol. This study found fluphenazine provided better tic control and fewer side effects for most patients.

    Area of Science:

    • Neurology
    • Pharmacology

    Background:

    • Multiple tic disorder presents challenges in treatment, particularly for patients intolerant to standard therapies like haloperidol.
    • Dose-limiting side effects of haloperidol necessitate exploring alternative therapeutic options.

    Purpose of the Study:

    • To evaluate the efficacy and tolerability of fluphenazine hydrochloride in patients with multiple tic disorder who experienced adverse effects from haloperidol.

    Main Methods:

    • A five-year study involving 21 patients diagnosed with multiple tic disorder.
    • Patients were treated with fluphenazine hydrochloride after demonstrating intolerance to haloperidol therapy.

    Main Results:

    • Sixteen out of 21 patients reported fewer side effects with fluphenazine hydrochloride.

    Related Experiment Videos

  • Eleven patients experienced better tic control, and five had equivalent control compared to haloperidol.

    • Conclusions:

    • Fluphenazine hydrochloride is a viable and effective treatment for multiple tic disorder.
    • It offers a favorable side effect profile for patients experiencing dose-limiting adverse events with haloperidol.