Methylcellulose, a viscous cushioning material in ophthalmic surgery

Methylcellulose has been used since 1976 to prevent damage to the corneal endothelium during operations for implantation of intraocular lenses. With a 2 per cent solution of methylcellulose it is possible to maintain a space between the cornea and iris even if vitreous pressure is present to operate without risk to the corneal endothelium. This paper demonstrates the safety of the intraocular use of methylcellulose based on the results of over 700 operations. The substance is cheap, universally available, and can be easily prepared for intraocular use.