Topical carbenoxolone sodium in the management of herpes simplex infection

Topical carbenoxolone was discovered by chance to be a highly effective anti-viral agent and was subsequently used in the management of Herpetic gingivostomatitis and recurrent Herpes labialis. A marked reduction in the healing time and pain associated with these lesions was noted. A discussion of the possible mechanisms of action of carbenoxolone is included.