Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Relative aversion thresholds for shock in infant mice.

Z M Nagy, J M Murphy, D Ray

    Developmental Psychobiology
    |May 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The macromolecules and lipid biomarkers as seen in the archean white mfolozi banded iron formation (BIF): Their biogenicity and possible implications for mars.

    Life sciences in space research·2026
    Same author

    Electric response of multiarm protein crystals.

    Physical review. E·2026
    Same author

    The Effects of Electric Fields on Protein Phase Behavior and Protein Crystallization Kinetics.

    The journal of physical chemistry letters·2024
    Same author

    Improved Tensor Current Limit from ^{8}B β Decay Including New Recoil-Order Calculations.

    Physical review letters·2024
    Same author

    Screening H3 Histone Acetylation in a Wild Bird, the House Sparrow (<i>Passer Domesticus</i>).

    Integrative organismal biology (Oxford, England)·2024
    Same author

    Direct Mass Measurements to Inform the Behavior of ^{128m}Sb in Nucleosynthetic Environments.

    Physical review letters·2024
    Same journal

    Low Pregnancy Cortisol and Infant Socioemotional Problems: The Mediating Role of Postpartum Depressive Symptoms.

    Developmental psychobiology·2026
    Same journal

    Bedding Type Modulates the Effects of Postpartum Resource Scarcity on Maternal Behavior in Rats.

    Developmental psychobiology·2026
    Same journal

    Inflammatory Stress Response During Pregnancy as a Connecting Link in Intergenerational Risk Cascades.

    Developmental psychobiology·2026
    Same journal

    Maternal Early Pregnancy Tetrahydrocannabinol (THC) Metabolites Correlate With Newborn Resting-State Functional Connectivity.

    Developmental psychobiology·2026
    Same journal

    Navigating Stress: Exploring the Role of Empathy in Caregiving.

    Developmental psychobiology·2026
    Same journal

    Children With Idiopathic Toe Walking Display Different Cortical Activation Patterns When Interpreting Tactile Sensation.

    Developmental psychobiology·2026
    See all related articles

    Mouse shock sensitivity remains consistent during early development. Researchers found that young mice aged 5 to 15 days exhibited similar responses to varying electric shock intensities, suggesting stable motivational properties of shock.

    Area of Science:

    • Neuroscience
    • Developmental Psychology
    • Animal Behavior

    Background:

    • Understanding the developmental trajectory of sensory processing is crucial for identifying age-related changes.
    • Investigating the aversiveness of stimuli like electric shock provides insights into pain perception and avoidance behaviors.
    • Early life experiences can shape neural pathways and behavioral responses.

    Purpose of the Study:

    • To assess the escape and avoidance responses of developing mice to varying intensities of electric shock.
    • To compare the effectiveness of constant current and fixed impedance shock sources in eliciting behavioral responses.
    • To determine if shock aversiveness changes across early developmental stages in mice.

    Main Methods:

    • A spatial-preference technique was employed to test mice aged 5, 7, 9, 11, 13, and 15 days.

    Related Experiment Videos

  • Electric shock intensities were administered using both AC constant current (0-0.2 mA) and fixed impedance (0-70 V) shock sources.
  • Escape and avoidance behaviors were recorded and analyzed across different ages and shock intensities.

    • Main Results:

    • Near-asymptotic escape and avoidance responses were observed at 0.1 mA for the constant current source and 50 V for the fixed impedance source.
    • Few age-related differences in the relative aversiveness of specific shock intensities were found.
    • The fixed impedance shock source resulted in more consistent avoidance behavior compared to the constant current source.

    Conclusions:

    • The motivational properties of electric shock appear to be stable throughout early mouse development (5-15 days of age).
    • The spatial-preference technique is a viable method for assessing age-related alterations in shock sensitivity.
    • This methodology can be utilized to study the impact of physiological or pharmacological manipulations on shock sensitivity during development.