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Related Experiment Videos

Collagenous colitis: a recently recognised reversible clinicopathological entity.

E R Eaves, P L Wallis, R L McIntyre

    Australian and New Zealand Journal of Medicine
    |December 1, 1983
    PubMed
    Summary

    This case report details collagenous colitis in an elderly man, presenting with watery diarrhea. The collagenous band was found throughout the colon and resolved with treatment, highlighting the need for biopsy in diagnosing this condition.

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    Area of Science:

    • Gastroenterology
    • Colorectal Diseases
    • Pathology

    Background:

    • Collagenous colitis is a rare condition characterized by a thickened subepithelial collagen layer in the colon.
    • Previous case reports predominantly involved middle-aged women and identified the collagenous band primarily in the left colon.

    Observation:

    • This report describes an unusual case of collagenous colitis in an 86-year-old male presenting with watery diarrhea.
    • The collagenous band was observed in both the right and left sides of the colon and was notably thicker than previously reported.
    • The condition resolved within three months post-biopsy, coinciding with symptomatic treatment.

    Findings:

    • The collagenous band in this case extended throughout the colon, unlike previous reports.
    • The patient experienced clinical improvement and resolution of the subepithelial collagenous band after treatment.

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  • This case represents the thickest collagenous band documented to date.

    • Implications:

    • Collagenous colitis should be considered in the differential diagnosis for patients presenting with watery diarrhea, regardless of age or sex.
    • Diagnosis requires histological confirmation via rectal or colonic biopsy.
    • The findings suggest that collagenous colitis can occur in elderly males and may present with a more extensive collagenous band.