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On use of chromogenic substrates for studies of coagulation inhibitors
Haemostasis
|January 1, 1978
Abstract:
Methodological problems encountered using chromogenic substrates on thrombin and Xa are discussed: (1) influence of substrate on inhibitor; (2) influence of heparin; (3) optimal concentrations; (4) specificity; (5) denatured enzymes, and (6) natural versus chromogenic substrates.