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Staphylococcus aureus endocarditis in Denmark 1976-1981.

N Frimodt-Møller, F Espersen, E Gutschik

    Scandinavian Journal of Infectious Diseases. Supplementum
    |January 1, 1983
    PubMed
    Summary
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    Staphylococcus aureus endocarditis has a high mortality rate of 71%, particularly in older patients and those with hospital-acquired infections or penicillin-resistant strains.

    Area of Science:

    • Infectious Diseases
    • Bacteriology
    • Clinical Medicine

    Background:

    • Staphylococcus aureus endocarditis is a severe infection.
    • Understanding risk factors and outcomes is crucial for patient management.

    Purpose of the Study:

    • To review clinical and bacteriological data of Staphylococcus aureus endocarditis cases.
    • To identify factors influencing mortality in these patients.

    Main Methods:

    • Retrospective review of 119 cases from Danish hospitals (1976-1981).
    • Analysis of clinical information, bacteriological data, and patient demographics.
    • Correlation of mortality with age, infection source, and antimicrobial resistance.

    Main Results:

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  • Overall mortality was 71%.
  • Significant mortality correlations found with advanced age, hospital-acquired infections (38% of cases), and penicillin resistance.
  • Skin infections were the most common entry point.
  • Phage type distribution was similar to other Staphylococcus aureus septicemia cases.

    • Conclusions:

    • Staphylococcus aureus endocarditis carries a high mortality risk.
    • Age, hospital-acquired infections, and penicillin resistance are key predictors of mortality.
    • Effective infection control and antimicrobial strategies are essential.