Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

End-point nystagmus.

L A Abel, L Parker, R B Daroff

    Investigative Ophthalmology & Visual Science
    |June 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Normal subjects exhibit varied responses to sustained lateral gaze. Some develop end-point nystagmus quickly, while others do not develop nystagmus even with prolonged deviation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Obstetric anaesthesia quality metrics: local implementation of data utilisation in the United Kingdom.

    International journal of obstetric anesthesia·2025
    Same author

    The public health community's use of social media for policy advocacy: a scoping review and suggestions to advance the field.

    Public health·2021
    Same author

    Current concepts in the management of ankle arthritis.

    Journal of clinical orthopaedics and trauma·2020
    Same author

    Acute continuous moderate-intensity exercise, but not low-volume high-intensity interval exercise, attenuates postprandial suppression of circulating osteocalcin in young overweight and obese adults.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
    Same author

    Cohort Profile: The Atlantic Partnership for Tomorrow's Health (Atlantic PATH) Study.

    International journal of epidemiology·2017
    Same author

    Atopic dermatitis and risk of hypertension, type 2 diabetes, myocardial infarction and stroke in a cross-sectional analysis from the Canadian Partnership for Tomorrow Project.

    The British journal of dermatology·2017
    Same journal

    Loss of ATRAID in Late-Onset, Non-Syndromic Retinitis Pigmentosa.

    Investigative ophthalmology & visual science·2026
    Same journal

    Whole-Exome Analysis Identifies Candidate Genes Associated With Diabetic Retinopathy.

    Investigative ophthalmology & visual science·2026
    Same journal

    Antiseptic Efficacy and Ocular Surface Toxicity of Povidone-Iodine and Chlorhexidine for Endophthalmitis Isolates.

    Investigative ophthalmology & visual science·2026
    Same journal

    Ocular IL-1α/IFN-γ Delay the Corneal Wound Healing in Rheumatoid Arthritis Through Mitochondrial Dysfunction and NLRP3 Inflammasome Activation.

    Investigative ophthalmology & visual science·2026
    Same journal

    New Guidelines for Ophthalmic Genetic Studies.

    Investigative ophthalmology & visual science·2026
    Same journal

    Genomic Copy Number Variants Associated With Strabismus and Amblyopia in the All of Us Research Program.

    Investigative ophthalmology & visual science·2026
    See all related articles

    Area of Science:

    • Ophthalmology
    • Neuroscience
    • Physiology

    Background:

    • End-point nystagmus is an involuntary eye movement observed during sustained gaze.
    • Understanding the development and characteristics of end-point nystagmus is crucial for diagnosing certain neurological and ophthalmological conditions.

    Purpose of the Study:

    • To investigate the occurrence and characteristics of end-point nystagmus in normal subjects during sustained lateral gaze.
    • To analyze the latency and waveform of nystagmus in relation to the degree and duration of eye deviation.

    Main Methods:

    • Infrared oculography was utilized to record eye movements.
    • Twelve healthy subjects participated in the study.
    • Subjects maintained fixation on a target light during sustained lateral gaze at various degrees of deviation for extended periods.

    Related Experiment Videos

    Main Results:

    • Five subjects did not develop nystagmus despite deviations up to 40 degrees for 4-5 minutes.
    • Six subjects developed nystagmus shortly after reaching deviated positions.
    • Nystagmus onset varied, with some developing it at 20 degrees deviation and others exhibiting 'fatigue' nystagmus after prolonged fixation.
    • The slow-phase waveform of the nystagmus was predominantly linear.

    Conclusions:

    • Individual responses to sustained lateral gaze vary significantly in healthy individuals.
    • The development of end-point nystagmus is not uniform and can be influenced by deviation magnitude and fixation duration.
    • The linear waveform observed suggests specific neural control mechanisms during sustained eccentric gaze.