Intercellular junctions in odontoblasts of the rat incisor studied with freeze-fracture

The morphology and distribution of various types of intercellular junctions were investigated in young odontoblasts. Gap junctions were found between odontoblasts as well as between odontoblasts and fibroblasts in the dental pulp. The junctions between odontoblasts were larger and more numerous than those between odontoblast and fibroblast, suggesting that the former may play an important role in regulating cellular activity and the latter may provide a pathway of low electrical resistance between odontoblast and nerve fibres. Irregularly-shaped gap junctions appeared as small aggregations of particles associated with a particle-free area and may indicate that the junction might not yet have been completely assembled. Tight junctions were observed at the distal ends of the young odontoblasts, arranged to form small maculae or faciae occludentes rather than belt-like zonulae. It is therefore not likely that the junction contributes to barrier function in the young odontoblasts. Although structures resembling typical desmosome were recognizable, this type of junction in odontoblasts is properly termed a desmosome-like junction from its morphological peculiarities.