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The hematocrit-electrolyte-concentration-apparatus (HECA).

H Kiesewetter, C Mrowietz, H Lazar

    Biorheology. Supplement : the Official Journal of the International Society of Biorheology
    |January 1, 1984
    PubMed
    Summary
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    A new instrument simultaneously measures hematocrit and total electrolyte concentration in blood and plasma. This device allows for accurate hematocrit correction, improving diagnostic capabilities for patients.

    Area of Science:

    • Biomedical Engineering
    • Clinical Chemistry
    • Hematology

    Background:

    • Accurate hematocrit measurement is crucial for clinical diagnostics.
    • Electrolyte concentration can affect hematocrit readings.
    • A need exists for simultaneous measurement and correction.

    Purpose of the Study:

    • To develop and evaluate an instrument for simultaneous hematocrit and total electrolyte concentration determination.
    • To enable correction of hematocrit values based on electrolyte fluctuations.

    Main Methods:

    • Development of a novel analytical instrument.
    • Testing with physiological and rigid erythrocyte suspensions.
    • Validation using plasma with varying electrolyte concentrations.

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    Main Results:

    • Successful simultaneous measurement of hematocrit and total electrolytes.
    • Demonstrated ability to correct hematocrit for electrolyte variations.
    • Pilot studies confirmed device performance on various samples.

    Conclusions:

    • The developed instrument provides accurate, simultaneous hematocrit and electrolyte measurements.
    • This technology offers potential for improved blood analysis, particularly for hemodialysis patients.
    • Future applications include clinical use in monitoring hemodialysis patients.