Mandibular myelosarcoma (chloroma): primary oral manifestation of promyelocytic leukemia

The case of a 35-year-old female patient with primary mandibular manifestation of myelosarcoma (chloroma) is reported. The clinical course and diagnostic and therapeutic measures are described. Myelosarcomas are rare and are considered specific lesions of an acute myeloid leukemia. In addition to systemic leukemia therapy, myelosarcomas frequently have to be treated surgically or by irradiation because of their specific tumor localizations.