Angioglomoid tumour of the mandible. A case report

A case of an angioglomoid tumour of bone occurring in the mandible is presented. The lesion is characterized by epithelioid and endothelioid cells that exhibit single and multilayered rings with a central signet ring-like cell suggesting vascular differentiation. These cells are arranged in strands and nests that are dispersed in a myxoid stroma. Radical resection of the involved mandibular bone was followed by a recurrence of the tumour in the interposed graft after 7 years. A second radical operation provided permanent cure as is demonstrated by a disease-free interval of 10 years. Histological features permitting the differentiation from other central jaw tumours are discussed.