[HLA antigens in systemic lupus erythematosus patients]

A study was made of the rate of HLA system antigens in 75 patients with different clinical versions and immuno-pathological manifestations of systemic lupus erythematosus (SLE). A total of 350 normal subjects comprised the control group. During SLE, a high rate of DNW3, B8 and AI antigens was revealed. Associative relations were established between individual clinical syndromes of SLE and immuno-pathological manifestations of the disease and definite antigens of the HLA system. The results of typing HLA system antigens can be used as additional criteria of SLE diagnosis, disease prediction, and choice of adequate therapy schemes.