Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Familial idiopathic membranous glomerulonephritis.

D Vasmant, K Murnaghan, A Bensman

    The International Journal of Pediatric Nephrology
    |December 1, 1984
    PubMed
    Summary

    Familial membranous glomerulonephritis, a rare kidney disease, was observed in two brothers with identical HLA antigens. This suggests a potential genetic predisposition to developing this condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effectiveness of Self-Help Interventions to Reduce Work Disability: A Rapid Mixed Methods Systematic Review.

    Journal of occupational rehabilitation·2026
    Same author

    Reliability and validity of self-reported questionnaires to measure pain and disability in adults with neck pain and its associated disorders: part 3-a systematic review from the CADRE Collaboration.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2019
    Same author

    Reliability and validity of clinical tests to assess posture, pain location, and cervical spine mobility in adults with neck pain and its associated disorders: Part 4. A systematic review from the cervical assessment and diagnosis research evaluation (CADRE) collaboration.

    Musculoskeletal science & practice·2018
    Same author

    Validity and reliability of clinical prediction rules used to screen for cervical spine injury in alert low-risk patients with blunt trauma to the neck: part 2. A systematic review from the Cervical Assessment and Diagnosis Research Evaluation (CADRE) Collaboration.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2017
    Same author

    Reliability and validity of clinical tests to assess the anatomical integrity of the cervical spine in adults with neck pain and its associated disorders: Part 1-A systematic review from the Cervical Assessment and Diagnosis Research Evaluation (CADRE) Collaboration.

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2017
    Same author

    Measures to prevent transfusion-related acute lung injury (TRALI).

    Vox sanguinis·2012

    Area of Science:

    • Nephrology
    • Immunogenetics

    Background:

    • Idiopathic membranous glomerulonephritis (IMGN) is a leading cause of nephrotic syndrome in adults.
    • The etiology of IMGN is largely unknown, with autoimmune factors suspected.

    Observation:

    • Two brothers presented with clinically and histologically confirmed idiopathic membranous glomerulonephritis.
    • Both siblings shared identical Human Leukocyte Antigen (HLA) serotypes.

    Findings:

    • This case represents the first documented instance of familial membranous glomerulonephritis.
    • The identical HLA antigens in affected siblings suggest a potential genetic susceptibility locus for IMGN.

    Implications:

    • Identifies a potential genetic component in the pathogenesis of idiopathic membranous glomerulonephritis.
    • Highlights the importance of family history in evaluating patients with IMGN.
    • May guide future research into specific HLA alleles associated with familial IMGN.

    Related Experiment Videos