Primary malignant haemangiopericytoma of the larynx (a case report with autopsy)

This is a report of an exceptional case of haemangiopericytoma of the larynx, which occurred in a 50-year-old male patient. Histological examination of biopsy fragments allowed us to make the correct diagnosis, later confirmed at autopsy. From a comprehensive review of the world literature on haemangiopericytomas, it appears that cases of indisputable well-documented laryngeal occurrence of the neoplasm amount to two only, including the present case. The morphological pattern, histogenesis, biological behaviour and therapy of the tumour, as well as differential diagnosis from other lesions, are discussed.