Fertility rate after hysterosalpingography with Sinografin

Area of Science:

• Reproductive Medicine
• Diagnostic Imaging

Background:

• Hysterosalpingography (HSG) is a diagnostic procedure for infertility.
• The use of Sinografin for HSG has increased following Salpix discontinuation.
• Pregnancy rates after Sinografin HSG were previously unreported.

Purpose of the Study:

• To evaluate the pregnancy rate in patients undergoing hysterosalpingography with Sinografin.
• To compare pregnancy rates with and without adjunctive therapy.

Main Methods:

• A study of 156 patients undergoing hysterosalpingography with Sinografin.
• Analysis of pregnancy rates based on procedure type (HSG only vs. HSG with adjunctive therapy).

Main Results:

• The overall pregnancy rate after Sinografin HSG was 10.9%.
• Patients receiving adjunctive therapy had a significantly higher pregnancy rate of 26.3%.
• Results are comparable to water-soluble contrast but lower than oil-soluble contrast.

Conclusions:

• Sinografin hysterosalpingography is associated with a notable pregnancy rate, particularly when combined with adjunctive therapy.
• The findings support the continued use of Sinografin in infertility evaluations.
• Further research may explore optimal adjunctive therapies to enhance conception rates.