Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Suprasellar germinoma.

J Takeuchi, H Handa, I Nagata

    Journal of Neurosurgery
    |July 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Suprasellar germinomas present with diabetes insipidus, visual issues, and pituitary dysfunction. These tumors are highly responsive to radiation therapy, with significant tumor reduction observed after low-dose irradiation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Cooperative transcription activation between Ad1, a CRE-like element, and other elements in the CYP11B gene promoter.

    Journal of biochemistry·1992
    Same author

    Transcriptional regulation by a point mutant of adenovirus-2 E1a product lacking DNA binding activity.

    The Journal of biological chemistry·1992
    Same author

    [Regulation of DNA replication and gene expression of adenovirus].

    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme·1992
    Same author

    Direct purification of multiple ATF/E4TF3 polypeptides from HeLa cell crude nuclear extracts using DNA affinity latex particles.

    Analytical biochemistry·1992
    Same author

    RNA editing of atp6 transcripts from male-sterile and normal cytoplasms of rapeseed (Brassica napus L.).

    FEBS letters·1992
    Same author

    A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s.

    The Journal of biological chemistry·1992
    Same journal

    Extent of resection as an independent predictor of survival for patients with glioblastoma as defined by the new WHO 2021 classification.

    Journal of neurosurgery·2026
    Same journal

    Surgical treatment of schwannomas around the tarsal tunnel: a case series of 40 patients and systematic review of the literature.

    Journal of neurosurgery·2026
    Same journal

    Direct targeting for focused ultrasound thalamotomy in the treatment of movement disorders.

    Journal of neurosurgery·2026
    Same journal

    Development and internal validation of the Meningioma Functional Outcome Risk and Counseling Estimator 6 score, a point-based prognostic tool for predicting 6-week functional independence after intracranial meningioma resection.

    Journal of neurosurgery·2026
    Same journal

    Connectional anatomy of the cerebellum: dentate nucleus and cerebellar peduncles from a surgical perspective.

    Journal of neurosurgery·2026
    Same journal

    Press releases in neurosurgery: is scientific accuracy compromised in public reporting of neurosurgery research?

    Journal of neurosurgery·2026
    See all related articles

    Area of Science:

    • Neuro-oncology
    • Endocrinology
    • Radiology

    Background:

    • Intracranial germinomas and teratomas show higher incidence in Japan.
    • Germinomas in pineal, third, and lateral ventricles predominantly affect males.
    • Suprasellar germinomas exhibit a balanced male:female ratio (1:1).

    Purpose of the Study:

    • To review the clinical features of suprasellar germinoma.
    • To highlight key diagnostic and therapeutic aspects of this rare tumor.

    Main Methods:

    • Retrospective review of 18 clinical cases of suprasellar germinoma.
    • Analysis of clinical presentation, neuroradiological findings, and treatment response.

    Main Results:

    • Common symptoms include diabetes insipidus, visual disturbances, and pituitary dysfunction (hypopituitarism or hormonal elevation).

    Related Experiment Videos

  • Neuroradiological examination typically reveals a suprasellar mass.
  • Suprasellar germinomas demonstrated high sensitivity to radiotherapy, with rapid tumor regression after as little as 1200 rads.

    • Conclusions:

    • Suprasellar germinomas have distinct clinical features and a unique gender distribution compared to other intracranial germinomas.
    • Early diagnosis via neuroradiology and prompt radiotherapy are crucial for effective management.
    • Radiotherapy is a highly effective treatment modality for suprasellar germinomas.