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A colony-stimulating-factor-producing cell line derived from mouse bone marrow cells transfected with adenovirus DNA
Gan
|June 1, 1983
Abstract:
A unique fibroblastoid cell line, BMA1, has been established from bone marrow cells of a DDY mouse transfected with adenovirus 5 DNA. BMA1 cells expressed adenoviral early antigens and BMA1-conditioned medium contained mouse granulocyte/macrophage colony-stimulating factor(s). The DNA transfection technique may be useful in establishing cell lines from bone marrow and analyzing the regulation of hemopoiesis.