Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Shunts for portal hypertension.

J L Weese, C E Yale, J R Pellett

    The American Surgeon
    |July 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Indiana pouch urinary diversion for adenocarcinoma developing after ureterosigmoidostomy.

    The Journal of urology·2001
    Same author

    Neoadjuvant chemotherapy, radical resection with intraoperative radiation therapy (IORT): improved treatment for gastric adenocarcinoma.

    Surgery·2000
    Same author

    Mesh inguinodynia: a new clinical syndrome after inguinal herniorrhaphy?

    Journal of the American College of Surgeons·1998
    Same author

    Tertiary hyperparathyroidism after renal transplantation: surgical strategy.

    Surgery·1998
    Same author

    Physiologic evaluation and surgical management of failed ileoanal pouch.

    Diseases of the colon and rectum·1998
    Same author

    Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: an Eastern Cooperative Oncology Group Study.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology·1998

    Portasystemic shunts are effective for portal hypertension, but rebleeding suggests shunt occlusion. Encephalopathy risk increases with continued alcohol consumption, especially in Child B and C patients.

    Area of Science:

    • Gastroenterology
    • Hepatology
    • Surgical Gastroenterology

    Background:

    • Portal hypertension is a serious complication of liver disease, often leading to life-threatening variceal bleeding.
    • Portasystemic shunts have been a primary surgical intervention for managing portal hypertension and its complications.

    Purpose of the Study:

    • To evaluate the outcomes of various portasystemic shunt procedures in patients with portal hypertension.
    • To assess the relationship between shunt type, patient condition (Child classification), and postoperative complications such as rebleeding and encephalopathy.

    Main Methods:

    • A retrospective analysis of 95 portasystemic shunts performed between 1963 and 1981.
    • Procedures included Warren, Linton, mesocaval, and portacaval shunts.
    • Patient outcomes were analyzed based on Child classification, operative mortality, survival rates, rebleeding, and encephalopathy.

    Related Experiment Videos

    Main Results:

    • Operative mortality varied significantly with Child classification (5.5% for A, 16.2% for B, 36.3% for C).
    • Five-year survival rates were 74% for Child A, 17.4% for B, and 26.3% for C.
    • Rebleeding in 15.7% of patients was often associated with shunt occlusion.
    • Postoperative encephalopathy was strongly correlated with continued alcohol consumption in alcoholic liver disease patients.

    Conclusions:

    • Portasystemic shunts can be performed with acceptable morbidity and mortality, though outcomes are heavily influenced by patient's liver function (Child class).
    • Rebleeding typically indicates shunt occlusion, necessitating further investigation.
    • Encephalopathy post-shunting is often linked to continued alcohol abuse.
    • Survival rates for Child B and C patients are poor, suggesting consideration of alternative treatments for these high-risk individuals.