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[Isolation and purification of penicillinase from Francisella tularensis]
Abstract:
beta-Lactamase was isolated from the cells of a penicillinase-producing strain of the tularemia causative agent. It was purified 100 times. By its properties (the substrate profile, Km, temperature optimum and thermostability) beta-lactamase differed from penicillinases isolated from other sources.