Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microphallus: clinical and endocrinological characteristics.

T D Allen

    The Journal of Urology
    |June 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A small plant industrial eye program.

    Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology·2010
    Same author

    The value of the complete routine examination in ophthalmological practice.

    Archivos. Asociacion para Evitar la Ceguera en Mexico·2010
    Same author

    Fundamentals of ophthalmologic office routine.

    Medical record and annals·2010
    Same author

    Refraction with special reference to presbyopia.

    Medical record and annals·2010
    Same author

    Managing the glaucomatous patient.

    Medical record and annals·2010
    Same author

    A protocol for isolating Xenopus oocyte nuclear envelope for visualization and characterization by scanning electron microscopy (SEM) or transmission electron microscopy (TEM).

    Nature protocols·2007

    This study reviews 15 males with microphallus, finding defective hypothalamic function. Early testosterone treatment is recommended for optimal hyperplastic response in young patients with small genitalia.

    Area of Science:

    • Pediatric Endocrinology
    • Neuroendocrinology
    • Human Sexual Development

    Background:

    • Microphallus, characterized by small but normally formed external genitalia, affects male subjects.
    • This condition can occur in isolation or be associated with central nervous system (CNS) defects.
    • Understanding the underlying endocrine and clinical features is crucial for effective management.

    Purpose of the Study:

    • To review the clinical and endocrinological features of male subjects with microphallus.
    • To investigate potential differences between isolated microphallus and microphallus associated with CNS defects.
    • To evaluate the endocrine data and treatment implications for microphallus.

    Main Methods:

    • Review of clinical data from 15 male subjects diagnosed with microphallus.

    Related Experiment Videos

  • Analysis of endocrinological profiles in patients with isolated microphallus and those with associated CNS defects.
  • Correlation of endocrine findings with clinical presentation.

    • Main Results:

    • All 15 subjects presented with small but normally formed external genitalia (microphallus).
    • Nine patients had simple microphallus; six exhibited associated central nervous system defects.
    • Endocrine data were consistent across both groups, indicating defective hypothalamic function.

    Conclusions:

    • Defective hypothalamic function is a key endocrinological feature in males with microphallus.
    • Parenteral testosterone is the current treatment of choice for microphallus.
    • Early initiation of testosterone therapy in childhood is recommended to maximize penile growth potential.