The effect of charatoxin, 4-methylthio-1,2-dithiolane, on the frog sartorius neuromuscular junction

The insecticide 4-methylthio-1,2-dithiolane, named charatoxin, blocks the frog muscular twitches elicited through the neuromuscular junction. The activity level and the course of inhibition is comparable to that of 4-dimethyl-amino-1,2-dithiolane, nereistoxin.