Increase of lymphocytic H-Y antigen in female 21-hydroxylase deficiency

H-Y antigen was found to be increased in lymphocytes from 10 female 21-hydroxylase deficiencies, suggesting a correlation between the degree of virilization of these patients and their H-Y + lymphocytes proportions. Furthermore, these findings demonstrate the ability of a 46,XX female subject to produce, in some circumstances, an excess of H-Y antigen.